Description

Antibiotic Discovery and Development – First Edition

Antibiotic Discovery and Development is a comprehensive resource that examines the scientific, technical, and strategic processes involved in discovering and developing new antibacterial drugs. Edited by Thomas J. Dougherty and Michael J. Pucci, this book addresses the urgent global need for novel antibiotics in the face of rising antimicrobial resistance.

The book covers the full pipeline of antibiotic development, including target identification, lead discovery, medicinal chemistry, pharmacokinetics, toxicity testing, and clinical trial design. It also explores modern approaches such as genomics-driven discovery, high-throughput screening, natural product research, and structure-based drug design.

In addition to scientific foundations, the text discusses regulatory challenges, economic considerations, and industry perspectives that influence antibiotic development today. Case studies and expert insights provide valuable context for understanding both successful and unsuccessful drug development programs.

This book is ideal for microbiologists, pharmacologists, medicinal chemists, pharmaceutical scientists, researchers, and graduate students interested in antimicrobial drug discovery and development.